ClinicalKey Latest Issue: Annals of Allergy, Asthma & Immunology https://www.clinicalkey.com/dura/browse/journalIssue/10811206 Content from the latest issue of Annals of Allergy, Asthma & Immunology. From the pages of AllergyWatch https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002942 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 406-408 | Joshi, Shyam R., MD; Fineman, Stanley M., MD; Lee, Gerald B., MD;...<br/>For this edition of “From the pages of AllergyWatch”, I have selected articles from recent issues of AllergyWatch related to shared decision-making. The first article is from the Journal of the American Medical Association on the development of a ... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002942 Remibrutinib impact on disease control, sleep, and quality of life https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002711 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 349-356.e5 | Mosnaim, Giselle, MD; Saini, Sarbjit, MD; Lebwohl, Mark, MD;...<br/>AbstractBackgroundChronic spontaneous urticaria (CSU) substantially reduces patients' quality of life (QoL); therefore, it is crucial to include QoL-related patient-reported outcome measures when assessing treatment efficacy. ObjectiveTo evaluate ... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002711 Shared decision-making and integrative medicine in the allergist’s office https://www.clinicalkey.com/playContent/1-s2.0-S1081120626000979 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 272-273 | Soffer, Gary K., MD; Marshall, Gailen D., MD, PhD<br/>“Integrative medicine is just good medicine.”—Andrew Weil The health care landscape has seen a seismic shift in the past several years in many areas of practice. There is growing concern about many aspects of conventional medical care and increasi... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626000979 Guidelines and shared decision-making for disruptive innovations in allergy https://www.clinicalkey.com/playContent/1-s2.0-S1081120626000542 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 274-275 | Golden, David B.K., MDCM<br/>Innovation can be so disruptive. OFC, OIT, SLIT, SMART: OMG! And now nasal epinephrine? We are not in Kansas anymore. Innovations are described as “disruptive” when they recognize and fill a gap in existing products or technologies in such a succe... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626000542 Patient and caregiver perspectives on threshold-based precautionary allergen labeling https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002000 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 362-367.e2 | Madireddy, Shreaya, BS; Milliron, Chloe, BS; Wong, Sharon, Med;...<br/>AbstractBackgroundPrecautionary allergen labeling (PAL), such as “may contain” statements, remains unregulated in the United States, despite its widespread use and importance for individuals with food allergies. ObjectiveTo explore the perspective... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002000 Improved asthma outcomes with dupilumab plus medium-dose inhaled corticosteroids vs placebo plus high-dose inhaled corticosteroids https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002231 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 320-328 | Busse, William W., MD; Castro, Mario, MD; Lugogo, Njira L., MD;...<br/>AbstractBackgroundEscalating from medium-dose inhaled corticosteroid (ICS) to high-dose ICS in patients with asthma offers limited clinical benefit. ObjectiveTo assess the advantages of adding dupilumab to medium-dose ICS vs continuing high-dose I... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002231 American College of Allergy, Asthma and Immunology (ACAAI)/American Academy of Pediatrics (AAP) symposium—What was served in the past year: Food allergy nontreatment https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002164 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 314-317 | Bingemann, Theresa A., MD<br/>AbstractFood allergies are increasing, with 1 of 13 children in the United States affected. This article discusses articles chosen by the author for inclusion in the American College of Allergy, Asthma and Immunology/American Academy of Pediatrics... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002164 Depemokimab reduces asthma exacerbations similarly to other biologics https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002188 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 329-339.e7 | Bourdin, Arnaud, MD; Pavord, Ian D., FMedSci; Ballew, Nicholas, PhD;...<br/>AbstractBackgroundDepemokimab is the first ultra–long-acting biologic, with efficacy and safety recently reported in the Phase III SWIFT-1/-2 studies, which included patients with type 2 asthma. ObjectiveTo estimate the relative efficacy and safet... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002188 Safety and efficacy of three office-based egg oral immunotherapy protocols https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002401 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 357-361 | Buckey, Timothy M., MD, MBE; Giannì, Giuliana, MD; Hanna, Elizabeth, MSN, RN, CPNP;...<br/>AbstractBackgroundEgg allergy is one of the most common IgE-mediated food allergies. There is no treatment approved by the US Food and Drug Administration that allows the liberalization of egg into the diet. Studies have shown that oral immunother... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002401 After the escalator https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002310 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 300-313 | Gronnier, Morgane, MD; Ramakrishnan, Sanjay, MD, PhD; Beasley, Richard W., DSc;...<br/>AbstractAsthma, the most common chronic respiratory disease, is characterized by variable symptoms, airflow limitation, and airway inflammation. Current management relies largely on a symptom-focused stepwise escalation approach, which often leads... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002310 Nonsteroidal anti-inflammatory drugs in the treatment of uterine anaphylaxis https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002656 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 398-401 | Luu, Janet, DO; Abud, Edsel, MD, PhD; Namazy, Jennifer, MD;...<br/>Uterine anaphylaxis, or anaphylaxis presenting with severe uterine cramping or contractions, is a rare manifestation of anaphylaxis in females, categorized as grade 3 by the World Allergy Organization. Although the literature is limited regarding ... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002656 Unique and shared patterns of chemosensory dysfunction distinguish chronic COVID-19 and aspirin-exacerbated respiratory disease https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002619 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 340-348.e3 | Minichetti, Dante G., BA; Dharia, Tiffany, MD; Boyd, Amelia, BA;...<br/>AbstractBackgroundPersistent chemosensory dysfunction (CSD) occurs in both COVID‑19 and aspirin-exacerbated respiratory disease (AERD). The similarities and differences in the chemosensory experiences of these 2 conditions remain undefined and poo... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002619 Communication, compassion, and shared decision-making in allergy https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001171 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 282-290 | Abrams, Elissa M., MD, MPH, FRCPC, FAAAAI<br/>AbstractShared decision-making (SDM) is a structured approach to clinical care that integrates the best available evidence, clinician expertise, and patient values. Although SDM frameworks are well described, comparatively little attention has bee... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001171 Predictors for T cell receptor excision circles in infants without severe combined immunodeficiency or thymic aplasia/hypoplasia https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001225 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 380-386.e3 | Navalpakam, Aishwarya, MD; Hurden, Isabel, MPH; Lugt, Mark Vander, MD;...<br/>AbstractBackgroundAlthough developed to identify severe combined immunodeficiency (SCID), T cell receptor excision circle (TREC)–based newborn screening also detects T cell lymphopenia of varying etiologies. ObjectiveTo identify perinatal factors ... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001225 Racial differences in food allergy diagnostics https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001766 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 368-373.e1 | Detlor, Luke, BS; Bindon, Brittany, MD; Carr, Elizabeth, PhD;...<br/>AbstractBackgroundIn the United States, food allergy (FA) is more prevalent among Black children and adults than among White populations. The reason for this observed difference is unknown. ObjectiveTo propose that bias in FA testing contributes t... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001766 Enhanced clinical decision-making to optimize targeted gene panel testing for inborn errors of immunity https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001614 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 387-395.e9 | Udomkittivorakul, Natsumon, MD; Zhang, Jiahua, MD; Arora, Jyoti, MS;...<br/>AbstractBackgroundTargeted gene panels (TGPs) are frequently used to assess inborn errors of immunity (IEI) owing to the expanding knowledge of monogenic causes. Refining their clinical indications may enhance test yields. ObjectiveTo assess clini... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001614 Rapid drug desensitization in pediatric patients https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001997 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 374-379.e2 | Sze, Summer T.K.; Leung, Daniel, PhD; Nguyen, Alan A., MD;...<br/>AbstractBackgroundDrug hypersensitivity is often managed by drug desensitization, yet published data remain scarce in children. This study evaluated the safety and efficacy of rapid desensitization to chemotherapeutic agents, monoclonal antibodies... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001997 Precision medicine in atopic dermatitis https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002668 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 291-299 | Fonacier, Luz, MD; Mawhirt, Stephanie, DO; Stern, Heather, DO;...<br/>AbstractAtopic dermatitis (AD) is a chronic, multifactorial inflammatory skin disease characterized by barrier dysfunction, immune dysregulation, genetic predisposition, and environmental factors, including microbiome and allergens. As more is lea... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002668 Genetic testing for inborn errors of immunity: Improving the pretest probability https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002139 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 280-281 | Chinen, Javier, MD, PhD<br/>The recently updated practice parameters for inborn errors of immunity (IEI) discussed recommendations for genetic testing and reviewed the positive impact of genetic diagnosis in the management of IEI, acknowledging its increased accessibility in... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002139 Introducing the distinguished authors of 2026 https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002644 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 269-269 | Grayson, Mitchell H., MD<br/>This year marks the third year of the Annals Distinguished Authors program. , Through the generosity of the American College of Allergy, Asthma and Immunology (ACAAI), Annals is able to honor those in the Allergy and Immunology field who have chan... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002644 Table of Contents https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003777 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages A3-A5<br/>(no summary available) https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003777 Editorial Board https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003789 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages A7-A7<br/>(no summary available) https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003789 Differential rates of oral food challenges among patients of different races https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002899 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 276-277 | Singh, Tarandeep, DO; Bingemann, Theresa A., MD<br/>Food allergy (FA) is a common and increasingly prevalent condition in the United States . Over the past 2 decades, racial disparities in FA have become increasingly apparent, with higher rates of self-reported FAs observed among racial and ethnic ... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002899 Clinical communication, shared decision-making, and kindness as the penultimate therapeutic modality https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001274 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 270-271 | Shaker, Marcus S., MD, MS; Davis, Ray S., MD; Bukstein, Don, MD<br/>Clinical communication underpins medical care, with the clinician-patient relationship at its core. Shared decision-making (SDM), highlighted in this month’s Annals, is an important part of this process. SDM is one type of clinical communication, ... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626001274 Man’s best friend: A history https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002024 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 318-319 | Reigh, Erin L., MD, MS<br/>Unlabelled image dummy alt text Cartootorial: Patients with animal allergies often inquire about the efficacy of subcutaneous immunotherapy (SCIT) to help them tolerate a beloved pet. While SCIT for cat allergy has been shown to improve clinical o... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002024 Differences in gastrointestinal adverse event rates during oral immunotherapy https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002632 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 404-404 | Moraca, Payge, DO; Zhou, Guangying, BA, BS; Schaefer, Karla, RN;...<br/>We read, with interest, the article by Buckey et al, which evaluated the rates of gastrointestinal adverse events among patients undergoing oral immunotherapy (OIT) at the Children’s Hospital of Philadelphia. We performed a similar retrospective r... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002632 Information for Readers https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003765 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages A1-A1<br/>(no summary available) https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003765 Thoughts on the July issue of Annals https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003297 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 405-405 | Bellanti, Joseph A., MD<br/>I read with great interest the editorial by Spergel entitled, “Allergy Is More Than Type 2 Disease,” and the accompanying articles describing the overlap among atopic dermatitis, autoimmune disease, eosinophilic esophagitis, and inborn errors of i... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626003297 Longitudinal prescribing patterns of mammalian allergen immunotherapy across the US Military Health Care System from 2005 to 2024 https://www.clinicalkey.com/playContent/1-s2.0-S108112062600267X Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 401-403 | Pepper, Elizabeth A., DO; Schornack, Brandon J., DO; Zamani, Michael, MS;...<br/>Mammalian allergens are clinically important triggers of allergic rhinoconjunctivitis and asthma, arising from both companion animal ownership and occupational exposure. Occupational exposure causes mammalian allergy in veterinarians, laboratory w... https://www.clinicalkey.com/playContent/1-s2.0-S108112062600267X Interpreting abnormal severe combined immunodeficiency (SCID) newborn screens https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002723 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 278-279 | Katz, Alexis R., DO, MSc; Ward, Brant R., MD, PhD<br/>The introduction of newborn screening (NBS) for severe combined immunodeficiency (SCID) marked a revolution in the management of children with the disease and expanded our understanding of the epidemiology in unexpected ways. First introduced as a... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002723 Refining pediatric eczema severity assessment with Three-Item Severity score and Patient-Oriented Eczema Measure https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002930 Annals of Allergy, Asthma & Immunology, Volume 137, Issue 3, 2026 Sep, Pages 396-397 | Tsai, Serena Yun-Chen, MD, MMSc; Atwal, Sanmeet, MD; Ong, Peck Y., MD<br/>Children with atopic dermatitis (AD) often struggle with impaired daily functioning, persistent itch, emotional distress, and disturbed sleep. These impacts highlight the importance of the patient perspective in assessing disease severity. Yet, ex... https://www.clinicalkey.com/playContent/1-s2.0-S1081120626002930